This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GANAB-20-RE | 20 (40 μL) | 200 μL |  |
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| GANAB-20-OR | 20 (40 μL) | 200 μL |  |
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| GANAB-20-GO | 20 (40 μL) | 200 μL |  |
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| GANAB-20-GR | 20 (40 μL) | 200 μL |  |
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| GANAB-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016]
Gene Symbol : GANAB
Gene Name : Glucosidase II alpha subunit
Chromosome : CHR 11: 626,467,25-626,248,25
Locus : 11q12.3
Alt. Genes : LRPPRC
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