This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GBF1-20-RE | 20 (40 μL) | 200 μL |  |
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| GBF1-20-OR | 20 (40 μL) | 200 μL |  |
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| GBF1-20-GO | 20 (40 μL) | 200 μL |  |
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| GBF1-20-GR | 20 (40 μL) | 200 μL |  |
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| GBF1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Symbol : GBF1
Gene Name : Golgi brefeldin A resistant guanine nucleotide exchange factor 1
Chromosome : CHR 10: 102,245,497-102,382,898
Locus : 10q24.32
Alt. Genes : SGK2
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