This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer. [provided by RefSeq, Jul 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GDF10-20-RE | 20 (40 μL) | 200 μL |  |
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| GDF10-20-OR | 20 (40 μL) | 200 μL |  |
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| GDF10-20-GO | 20 (40 μL) | 200 μL |  |
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| GDF10-20-GR | 20 (40 μL) | 200 μL |  |
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| GDF10-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer. [provided by RefSeq, Jul 2016]
Gene Symbol : GDF10
Gene Name : Growth differentiation factor 10
Chromosome : CHR 10: 473,002,23-473,135,76
Locus : 10q11.22
Alt. Genes : FEM1B
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