This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
GDF7-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
GDF7-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
GDF7-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
GDF7-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
GDF7-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016]
Gene Symbol : GDF7
Gene Name : Growth differentiation factor 7
Chromosome : CHR 2: 206,666,63-206,714,89
Locus : 2p24.1
Alt. Genes : ATP6AP2
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.