GEMIN2 FISH Probe

This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
GEMIN2-20-RE 20 (40 μL) 200 μL color Request Pricing
GEMIN2-20-OR 20 (40 μL) 200 μL color Request Pricing
GEMIN2-20-GO 20 (40 μL) 200 μL color Request Pricing
GEMIN2-20-GR 20 (40 μL) 200 μL color Request Pricing
GEMIN2-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011]

Gene Details

Gene Symbol : GEMIN2

Gene Name : Gem nuclear organelle associated protein 2

Chromosome : CHR 14: 391,142,60-391,369,72

Locus : 14q21.1

Alt. Genes : HIPK3

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