This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GFI1B-20-RE | 20 (40 μL) | 200 μL |  |
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| GFI1B-20-OR | 20 (40 μL) | 200 μL |  |
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| GFI1B-20-GO | 20 (40 μL) | 200 μL |  |
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| GFI1B-20-GR | 20 (40 μL) | 200 μL |  |
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| GFI1B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
Gene Symbol : GFI1B
Gene Name : Growth factor independent 1B transcriptional repressor
Chromosome : CHR 9: 132,945,544-132,991,696
Locus : 9q34.13
Alt. Genes : ARPC2
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