Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
GFM2-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
GFM2-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
GFM2-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
GFM2-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
GFM2-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]
Gene Symbol : GFM2
Gene Name : G elongation factor mitochondrial 2
Chromosome : CHR 5: 747,673,70-747,212,03
Locus : 5q13.3
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