This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
GGA1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
GGA1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
GGA1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
GGA1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
GGA1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : GGA1
Gene Name : Golgi associated, gamma adaptin ear containing, ARF binding protein 1
Chromosome : CHR 22: 376,072,34-376,335,63
Locus : 22q13.1
Alt. Genes : ENAM
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