This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GGA2-20-RE | 20 (40 μL) | 200 μL |  |
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| GGA2-20-OR | 20 (40 μL) | 200 μL |  |
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| GGA2-20-GO | 20 (40 μL) | 200 μL |  |
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| GGA2-20-GR | 20 (40 μL) | 200 μL |  |
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| GGA2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008]
Gene Symbol : GGA2
Gene Name : Golgi associated, gamma adaptin ear containing, ARF binding protein 2
Chromosome : CHR 16: 235,104,93-234,635,41
Locus : 16p12.2
Alt. Genes : ABI2
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