This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GLRX-20-RE | 20 (40 μL) | 200 μL |  |
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| GLRX-20-OR | 20 (40 μL) | 200 μL |  |
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| GLRX-20-GO | 20 (40 μL) | 200 μL |  |
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| GLRX-20-GR | 20 (40 μL) | 200 μL |  |
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| GLRX-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]
Gene Symbol : GLRX
Gene Name : Glutaredoxin
Chromosome : CHR 5: 958,228,72-958,138,48
Locus : 5q15
Alt. Genes : LRPPRC
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