This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GLS-20-RE | 20 (40 μL) | 200 μL |  |
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| GLS-20-OR | 20 (40 μL) | 200 μL |  |
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| GLS-20-GO | 20 (40 μL) | 200 μL |  |
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| GLS-20-GR | 20 (40 μL) | 200 μL |  |
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| GLS-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Symbol : GLS
Gene Name : Glutaminase
Chromosome : CHR 2: 190,880,820-190,965,551
Locus : 2q32.2
Alt. Genes : ABI2
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