In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GMPS-20-RE | 20 (40 μL) | 200 μL |  |
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| GMPS-20-OR | 20 (40 μL) | 200 μL |  |
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| GMPS-20-GO | 20 (40 μL) | 200 μL |  |
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| GMPS-20-GR | 20 (40 μL) | 200 μL |  |
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| GMPS-20-AQ | 20 (40 μL) | 200 μL |  |
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In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008]
Gene Symbol : GMPS
Gene Name : Guanine monophosphate synthase
Chromosome : CHR 3: 155,869,429-155,943,678
Locus : 3q25.31
Alt. Genes : RAD50
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