G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GNG5-20-RE | 20 (40 μL) | 200 μL |  |
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| GNG5-20-OR | 20 (40 μL) | 200 μL |  |
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| GNG5-20-GO | 20 (40 μL) | 200 μL |  |
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| GNG5-20-GR | 20 (40 μL) | 200 μL |  |
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| GNG5-20-AQ | 20 (40 μL) | 200 μL |  |
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G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010]
Gene Symbol : GNG5
Gene Name : G protein subunit gamma 5
Chromosome : CHR 1: 845,065,78-844,983,22
Locus : 1p22.3
Alt. Genes : CLEC3A
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