In non-hominoid primates and non-mammalian vertebrates, the gonadotropin releasing hormone 2 receptor gene (GnRHR2) encodes a seven-transmembrane G-protein coupled receptor. However, in human, the corresponding reading frame contains a premature stop codon, which has been suggested to encode a selenocysteine residue, but there is no solid evidence for selenocysteine incorporation (PMID: 12538601). It appears that the human GnRHR2 transcription occurs but the gene does not likely produce a functional multi-transmembrane protein. A non-transcribed pseudogene of GnRHR2 is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GNRHR2-20-RE | 20 (40 μL) | 200 μL |  |
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| GNRHR2-20-OR | 20 (40 μL) | 200 μL |  |
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| GNRHR2-20-GO | 20 (40 μL) | 200 μL |  |
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| GNRHR2-20-GR | 20 (40 μL) | 200 μL |  |
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| GNRHR2-20-AQ | 20 (40 μL) | 200 μL |  |
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In non-hominoid primates and non-mammalian vertebrates, the gonadotropin releasing hormone 2 receptor gene (GnRHR2) encodes a seven-transmembrane G-protein coupled receptor. However, in human, the corresponding reading frame contains a premature stop codon, which has been suggested to encode a selenocysteine residue, but there is no solid evidence for selenocysteine incorporation (PMID: 12538601). It appears that the human GnRHR2 transcription occurs but the gene does not likely produce a functional multi-transmembrane protein. A non-transcribed pseudogene of GnRHR2 is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2013]
Gene Symbol : GNRHR2
Gene Name : Gonadotropin releasing hormone receptor 2 (pseudogene)
Chromosome : CHR 1: 145,919,012-145,925,340
Locus : 1q21.1
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