This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GP6-20-RE | 20 (40 μL) | 200 μL |  |
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| GP6-20-OR | 20 (40 μL) | 200 μL |  |
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| GP6-20-GO | 20 (40 μL) | 200 μL |  |
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| GP6-20-GR | 20 (40 μL) | 200 μL |  |
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| GP6-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Symbol : GP6
Gene Name : Glycoprotein VI platelet
Chromosome : CHR 19: 550,382,63-550,137,04
Locus : 19q13.42
Alt. Genes : CALCOCO2
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