This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GPBP1-20-RE | 20 (40 μL) | 200 μL |  |
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| GPBP1-20-OR | 20 (40 μL) | 200 μL |  |
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| GPBP1-20-GO | 20 (40 μL) | 200 μL |  |
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| GPBP1-20-GR | 20 (40 μL) | 200 μL |  |
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| GPBP1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
Gene Symbol : GPBP1
Gene Name : GC-rich promoter binding protein 1
Chromosome : CHR 5: 571,738,25-572,646,78
Locus : 5q11.2
Alt. Genes : CELA3A
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