The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GPNMB-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| GPNMB-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| GPNMB-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| GPNMB-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| GPNMB-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : GPNMB
Gene Name : Glycoprotein nmb
Chromosome : CHR 7: 232,462,05-232,751,09
Locus : 7p15.3
Alt. Genes : SGK2
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.