This gene encodes an integral membrane protein that belongs to the Class A rhodopsin superfamily of G protein coupled receptors. The encoded protein is expressed primarily in the central nervous system. A knockdown of the orthologous gene in rat is associated with a significant reduction in food intake and impaired decision making ability. Mutations in this gene are associated with schizophrenia, autism, and other neuropsychiatric disorders. The expression of this gene is activated by the glioma-associated oncogene homolog 1 transcription factor which, in turn, is activated by sonic hedgehog in normal and tumorigenic cells. [provided by RefSeq, Feb 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GPR153-20-RE | 20 (40 μL) | 200 μL |  |
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| GPR153-20-OR | 20 (40 μL) | 200 μL |  |
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| GPR153-20-GO | 20 (40 μL) | 200 μL |  |
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| GPR153-20-GR | 20 (40 μL) | 200 μL |  |
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| GPR153-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an integral membrane protein that belongs to the Class A rhodopsin superfamily of G protein coupled receptors. The encoded protein is expressed primarily in the central nervous system. A knockdown of the orthologous gene in rat is associated with a significant reduction in food intake and impaired decision making ability. Mutations in this gene are associated with schizophrenia, autism, and other neuropsychiatric disorders. The expression of this gene is activated by the glioma-associated oncogene homolog 1 transcription factor which, in turn, is activated by sonic hedgehog in normal and tumorigenic cells. [provided by RefSeq, Feb 2017]
Gene Symbol : GPR153
Gene Name : G protein-coupled receptor 153
Chromosome : CHR 1: 626,097,4-624,734,5
Locus : 1p36.31
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