This gene belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike several other characterized glutathione peroxidases, this enzyme is not a selenoprotein, lacking the selenocysteine residue. Thus, it is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GPX5-20-RE | 20 (40 μL) | 200 μL |  |
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| GPX5-20-OR | 20 (40 μL) | 200 μL |  |
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| GPX5-20-GO | 20 (40 μL) | 200 μL |  |
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| GPX5-20-GR | 20 (40 μL) | 200 μL |  |
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| GPX5-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike several other characterized glutathione peroxidases, this enzyme is not a selenoprotein, lacking the selenocysteine residue. Thus, it is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2016]
Gene Symbol : GPX5
Gene Name : Glutathione peroxidase 5
Chromosome : CHR 6: 285,260,11-285,349,50
Locus : 6p22.1
Alt. Genes : CALCOCO2
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