Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
GRIA3-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
GRIA3-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
GRIA3-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
GRIA3-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
GRIA3-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008]
Gene Symbol : GRIA3
Gene Name : Glutamate ionotropic receptor AMPA type subunit 3
Chromosome : CHR X: 123,184,242-123,490,914
Locus : Xq25
Alt. Genes : CLEC3A
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