Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GRIK1-20-RE | 20 (40 μL) | 200 μL |  |
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| GRIK1-20-OR | 20 (40 μL) | 200 μL |  |
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| GRIK1-20-GO | 20 (40 μL) | 200 μL |  |
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| GRIK1-20-GR | 20 (40 μL) | 200 μL |  |
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| GRIK1-20-AQ | 20 (40 μL) | 200 μL |  |
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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : GRIK1
Gene Name : Glutamate ionotropic receptor kainate type subunit 1
Chromosome : CHR 21: 299,400,51-295,369,32
Locus : 21q21.3
Alt. Genes : ZNF263
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