Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GRIK3-20-RE | 20 (40 μL) | 200 μL |  |
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| GRIK3-20-OR | 20 (40 μL) | 200 μL |  |
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| GRIK3-20-GO | 20 (40 μL) | 200 μL |  |
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| GRIK3-20-GR | 20 (40 μL) | 200 μL |  |
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| GRIK3-20-AQ | 20 (40 μL) | 200 μL |  |
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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq, Jul 2008]
Gene Symbol : GRIK3
Gene Name : Glutamate ionotropic receptor kainate type subunit 3
Chromosome : CHR 1: 370,342,42-367,955,26
Locus : 1p34.3
Alt. Genes : ENAM
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