This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GRK2-20-RE | 20 (40 μL) | 200 μL |  |
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| GRK2-20-OR | 20 (40 μL) | 200 μL |  |
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| GRK2-20-GO | 20 (40 μL) | 200 μL |  |
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| GRK2-20-GR | 20 (40 μL) | 200 μL |  |
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| GRK2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017]
Gene Symbol : GRK2
Gene Name : G protein-coupled receptor kinase 2
Chromosome : CHR 11: 672,664,19-672,865,57
Locus : 11q13.2
Alt. Genes : CHST4
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