RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GTF3C6-20-RE | 20 (40 μL) | 200 μL |  |
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| GTF3C6-20-OR | 20 (40 μL) | 200 μL |  |
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| GTF3C6-20-GO | 20 (40 μL) | 200 μL |  |
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| GTF3C6-20-GR | 20 (40 μL) | 200 μL |  |
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| GTF3C6-20-AQ | 20 (40 μL) | 200 μL |  |
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RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.[supplied by OMIM, Mar 2008]
Gene Symbol : GTF3C6
Gene Name : General transcription factor IIIC subunit 6
Chromosome : CHR 6: 110,958,559-110,967,887
Locus : 6q21
Alt. Genes : ENAM
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