Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GYPC-20-RE | 20 (40 μL) | 200 μL |  |
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| GYPC-20-OR | 20 (40 μL) | 200 μL |  |
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| GYPC-20-GO | 20 (40 μL) | 200 μL |  |
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| GYPC-20-GR | 20 (40 μL) | 200 μL |  |
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| GYPC-20-AQ | 20 (40 μL) | 200 μL |  |
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Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Gene Symbol : GYPC
Gene Name : Glycophorin C (Gerbich blood group)
Chromosome : CHR 2: 126,655,934-126,696,674
Locus : 2q14.3
Alt. Genes : EBI3
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