This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14. [provided by RefSeq, Nov 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GZMH-20-RE | 20 (40 μL) | 200 μL |  |
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| GZMH-20-OR | 20 (40 μL) | 200 μL |  |
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| GZMH-20-GO | 20 (40 μL) | 200 μL |  |
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| GZMH-20-GR | 20 (40 μL) | 200 μL |  |
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| GZMH-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14. [provided by RefSeq, Nov 2015]
Gene Symbol : GZMH
Gene Name : Granzyme H
Chromosome : CHR 14: 246,097,62-246,064,79
Locus : 14q12
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