Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GZMM-20-RE | 20 (40 μL) | 200 μL |  |
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| GZMM-20-OR | 20 (40 μL) | 200 μL |  |
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| GZMM-20-GO | 20 (40 μL) | 200 μL |  |
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| GZMM-20-GR | 20 (40 μL) | 200 μL |  |
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| GZMM-20-AQ | 20 (40 μL) | 200 μL |  |
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Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Symbol : GZMM
Gene Name : Granzyme M
Chromosome : CHR 19: 544,033-549,919
Locus : 19p13.3
Alt. Genes : STX6
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