Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
H3F3A-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
H3F3A-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
H3F3A-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
H3F3A-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
H3F3A-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family. [provided by RefSeq, Jul 2008]
Gene Symbol : H3F3A
Gene Name : H3 histone family member 3A
Chromosome : CHR 1: 226,062,706-226,072,001
Locus : 1q42.12
Alt. Genes : SLC25A13
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