The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HBB-20-RE | 20 (40 μL) | 200 μL |  |
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| HBB-20-OR | 20 (40 μL) | 200 μL |  |
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| HBB-20-GO | 20 (40 μL) | 200 μL |  |
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| HBB-20-GR | 20 (40 μL) | 200 μL |  |
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| HBB-20-AQ | 20 (40 μL) | 200 μL |  |
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The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
Gene Symbol : HBB
Gene Name : Hemoglobin subunit beta
Chromosome : CHR 11: 522,707,0-522,546,5
Locus : 11p15.4
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