The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HBD-20-RE | 20 (40 μL) | 200 μL |  |
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| HBD-20-OR | 20 (40 μL) | 200 μL |  |
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| HBD-20-GO | 20 (40 μL) | 200 μL |  |
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| HBD-20-GR | 20 (40 μL) | 200 μL |  |
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| HBD-20-AQ | 20 (40 μL) | 200 μL |  |
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The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia. [provided by RefSeq, Jul 2008]
Gene Symbol : HBD
Gene Name : Hemoglobin subunit delta
Chromosome : CHR 11: 523,462,7-523,282,8
Locus : 11p15.4
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