This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HCST-20-RE | 20 (40 μL) | 200 μL |  |
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| HCST-20-OR | 20 (40 μL) | 200 μL |  |
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| HCST-20-GO | 20 (40 μL) | 200 μL |  |
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| HCST-20-GR | 20 (40 μL) | 200 μL |  |
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| HCST-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol : HCST
Gene Name : Hematopoietic cell signal transducer
Chromosome : CHR 19: 359,023,64-359,042,70
Locus : 19q13.12
Alt. Genes : MPHOSPH9
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