Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
HDAC1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
HDAC1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
HDAC1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
HDAC1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
HDAC1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
Gene Symbol : HDAC1
Gene Name : Histone deacetylase 1
Chromosome : CHR 1: 322,921,02-323,336,27
Locus : 1p35.2-p35.1
Alt. Genes : OPTN
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