Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HDAC8-20-RE | 20 (40 μL) | 200 μL |  |
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| HDAC8-20-OR | 20 (40 μL) | 200 μL |  |
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| HDAC8-20-GO | 20 (40 μL) | 200 μL |  |
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| HDAC8-20-GR | 20 (40 μL) | 200 μL |  |
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| HDAC8-20-AQ | 20 (40 μL) | 200 μL |  |
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Symbol : HDAC8
Gene Name : Histone deacetylase 8
Chromosome : CHR X: 725,731,02-723,295,15
Locus : Xq13.1
Alt. Genes : ZNF263
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