This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. The protein includes an N-terminal PWWP domain that binds to methyl-lysine-containing histones, with specific binding of this protein to tri-methylated lysines 36 and 79 of histone H3, and di- and tri-methylated lysine 20 of histone H4. The protein functions in LEDGF/p75-independent HIV-1 replication by determining HIV-1 integration site selection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HDGFL2-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| HDGFL2-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| HDGFL2-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| HDGFL2-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| HDGFL2-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. The protein includes an N-terminal PWWP domain that binds to methyl-lysine-containing histones, with specific binding of this protein to tri-methylated lysines 36 and 79 of histone H3, and di- and tri-methylated lysine 20 of histone H4. The protein functions in LEDGF/p75-independent HIV-1 replication by determining HIV-1 integration site selection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Gene Symbol : HDGFL2
Gene Name : HDGF like 2
Chromosome : CHR 19: 447,219,5-450,221,9
Locus : 19p13.3
Alt. Genes : OPTN
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.