This gene belongs to the HERC gene family that encodes a group of unusually large proteins, which contain multiple structural domains. All members have at least 1 copy of an N-terminal region showing homology to the cell cycle regulator RCC1 and a C-terminal HECT (homologous to E6-AP C terminus) domain found in a number of E3 ubiquitin protein ligases. Genetic variations in this gene are associated with skin/hair/eye pigmentation variability. Multiple pseudogenes of this gene are located on chromosomes 15 and 16. [provided by RefSeq, Mar 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HERC2-20-RE | 20 (40 μL) | 200 μL |  |
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| HERC2-20-OR | 20 (40 μL) | 200 μL |  |
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| HERC2-20-GO | 20 (40 μL) | 200 μL |  |
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| HERC2-20-GR | 20 (40 μL) | 200 μL |  |
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| HERC2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene belongs to the HERC gene family that encodes a group of unusually large proteins, which contain multiple structural domains. All members have at least 1 copy of an N-terminal region showing homology to the cell cycle regulator RCC1 and a C-terminal HECT (homologous to E6-AP C terminus) domain found in a number of E3 ubiquitin protein ligases. Genetic variations in this gene are associated with skin/hair/eye pigmentation variability. Multiple pseudogenes of this gene are located on chromosomes 15 and 16. [provided by RefSeq, Mar 2012]
Gene Symbol : HERC2
Gene Name : HECT and RLD domain containing E3 ubiquitin protein ligase 2
Chromosome : CHR 15: 283,221,72-281,110,36
Locus : 15q13.1
Alt. Genes : RBM5
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