This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HEXIM2-20-RE | 20 (40 μL) | 200 μL |  |
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| HEXIM2-20-OR | 20 (40 μL) | 200 μL |  |
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| HEXIM2-20-GO | 20 (40 μL) | 200 μL |  |
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| HEXIM2-20-GR | 20 (40 μL) | 200 μL |  |
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| HEXIM2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Symbol : HEXIM2
Gene Name : Hexamethylene bisacetamide inducible 2
Chromosome : CHR 17: 451,601,73-451,700,39
Locus : 17q21.31
Alt. Genes : CHST4
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