Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
HIST3H3-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
HIST3H3-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
HIST3H3-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
HIST3H3-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
HIST3H3-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
Gene Symbol : HIST3H3
Gene Name : Histone cluster 3 H3
Chromosome : CHR 1: 228,425,324-228,424,844
Locus : 1q42.13
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