Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Aug 2015]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
HIST4H4-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
HIST4H4-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
HIST4H4-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
HIST4H4-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
HIST4H4-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Aug 2015]
Gene Symbol : HIST4H4
Gene Name : Histone cluster 4 H4
Chromosome : CHR 12: 147,711,30-147,707,19
Locus : 12p12.3
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