This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq, Jun 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HLA-DQA2-20-RE | 20 (40 μL) | 200 μL |  |
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| HLA-DQA2-20-OR | 20 (40 μL) | 200 μL |  |
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| HLA-DQA2-20-GO | 20 (40 μL) | 200 μL |  |
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| HLA-DQA2-20-GR | 20 (40 μL) | 200 μL |  |
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| HLA-DQA2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq, Jun 2010]
Gene Symbol : HLA-DQA2
Gene Name : Major histocompatibility complex, class II, DQ alpha 2
Chromosome : CHR 6: 327,413,85-327,468,86
Locus : 6p21.32
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