This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HLF-20-RE | 20 (40 μL) | 200 μL |  |
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| HLF-20-OR | 20 (40 μL) | 200 μL |  |
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| HLF-20-GO | 20 (40 μL) | 200 μL |  |
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| HLF-20-GR | 20 (40 μL) | 200 μL |  |
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| HLF-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : HLF
Gene Name : HLF, PAR bZIP transcription factor
Chromosome : CHR 17: 552,649,59-553,250,64
Locus : 17q22
Alt. Genes : MKRN3-AS1
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