The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HNF4A-20-RE | 20 (40 μL) | 200 μL |  |
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| HNF4A-20-OR | 20 (40 μL) | 200 μL |  |
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| HNF4A-20-GO | 20 (40 μL) | 200 μL |  |
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| HNF4A-20-GR | 20 (40 μL) | 200 μL |  |
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| HNF4A-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]
Gene Symbol : HNF4A
Gene Name : Hepatocyte nuclear factor 4 alpha
Chromosome : CHR 20: 443,558,00-444,328,44
Locus : 20q13.12
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