In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HOXA7-20-RE | 20 (40 μL) | 200 μL |  |
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| HOXA7-20-OR | 20 (40 μL) | 200 μL |  |
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| HOXA7-20-GO | 20 (40 μL) | 200 μL |  |
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| HOXA7-20-GR | 20 (40 μL) | 200 μL |  |
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| HOXA7-20-AQ | 20 (40 μL) | 200 μL |  |
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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila. [provided by RefSeq, Jul 2008]
Gene Symbol : HOXA7
Gene Name : Homeobox A7
Chromosome : CHR 7: 271,566,76-271,537,15
Locus : 7p15.2
Alt. Genes : TRIM28
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