This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HOXB4-20-RE | 20 (40 μL) | 200 μL |  |
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| HOXB4-20-OR | 20 (40 μL) | 200 μL |  |
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| HOXB4-20-GO | 20 (40 μL) | 200 μL |  |
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| HOXB4-20-GR | 20 (40 μL) | 200 μL |  |
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| HOXB4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq, Jul 2008]
Gene Symbol : HOXB4
Gene Name : Homeobox B4
Chromosome : CHR 17: 485,783,80-485,755,06
Locus : 17q21.32
Alt. Genes : RASA4
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