This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HOXB5-20-RE | 20 (40 μL) | 200 μL |  |
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| HOXB5-20-OR | 20 (40 μL) | 200 μL |  |
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| HOXB5-20-GO | 20 (40 μL) | 200 μL |  |
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| HOXB5-20-GR | 20 (40 μL) | 200 μL |  |
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| HOXB5-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008]
Gene Symbol : HOXB5
Gene Name : Homeobox B5
Chromosome : CHR 17: 485,937,40-485,912,56
Locus : 17q21.32
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