HOXD10 FISH Probe

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
HOXD10-20-RE 20 (40 μL) 200 μL color Request Pricing
HOXD10-20-OR 20 (40 μL) 200 μL color Request Pricing
HOXD10-20-GO 20 (40 μL) 200 μL color Request Pricing
HOXD10-20-GR 20 (40 μL) 200 μL color Request Pricing
HOXD10-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol : HOXD10

Gene Name : Homeobox D10

Chromosome : CHR 2: 176,116,763-176,119,941

Locus : 2q31.1

Alt. Genes : PREB

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