Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HSF4-20-RE | 20 (40 μL) | 200 μL |  |
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| HSF4-20-OR | 20 (40 μL) | 200 μL |  |
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| HSF4-20-GO | 20 (40 μL) | 200 μL |  |
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| HSF4-20-GR | 20 (40 μL) | 200 μL |  |
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| HSF4-20-AQ | 20 (40 μL) | 200 μL |  |
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Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : HSF4
Gene Name : Heat shock transcription factor 4
Chromosome : CHR 16: 671,633,84-671,699,44
Locus : 16q22.1
Alt. Genes : CELA3A
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