T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 [PubMed 12960172]).[supplied by OMIM, Mar 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
HSH2D-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
HSH2D-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
HSH2D-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
HSH2D-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
HSH2D-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 [PubMed 12960172]).[supplied by OMIM, Mar 2008]
Gene Symbol : HSH2D
Gene Name : Hematopoietic SH2 domain containing
Chromosome : CHR 19: 161,340,27-161,585,74
Locus : 19p13.11
Alt. Genes : CEBPZ
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