This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HTR2A-20-RE | 20 (40 μL) | 200 μL |  |
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| HTR2A-20-OR | 20 (40 μL) | 200 μL |  |
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| HTR2A-20-GO | 20 (40 μL) | 200 μL |  |
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| HTR2A-20-GR | 20 (40 μL) | 200 μL |  |
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| HTR2A-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Symbol : HTR2A
Gene Name : 5-hydroxytryptamine receptor 2A
Chromosome : CHR 13: 468,970,75-468,315,41
Locus : 13q14.2
Alt. Genes : OPTN
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