This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HTRA2-20-RE | 20 (40 μL) | 200 μL |  |
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| HTRA2-20-OR | 20 (40 μL) | 200 μL |  |
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| HTRA2-20-GO | 20 (40 μL) | 200 μL |  |
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| HTRA2-20-GR | 20 (40 μL) | 200 μL |  |
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| HTRA2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Gene Symbol : HTRA2
Gene Name : HtrA serine peptidase 2
Chromosome : CHR 2: 745,294,04-745,335,55
Locus : 2p13.1
Alt. Genes : AKAP9
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