Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IARS-20-RE | 20 (40 μL) | 200 μL |  |
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| IARS-20-OR | 20 (40 μL) | 200 μL |  |
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| IARS-20-GO | 20 (40 μL) | 200 μL |  |
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| IARS-20-GR | 20 (40 μL) | 200 μL |  |
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| IARS-20-AQ | 20 (40 μL) | 200 μL |  |
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Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]
Gene Symbol : IARS
Gene Name : Isoleucyl-tRNA synthetase
Chromosome : CHR 9: 922,937,55-922,102,06
Locus : 9q22.31
Alt. Genes : HIPK3
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